Clomiphene and Male Menopause

Can Clomiphene be used for male menopause? Like women, men experience a plunge in their levels of sex hormones as they age. But in men, the rate of these changes is quite dissimilar. With men, it’s much slower.

Levels of a man’s main sex hormone, the testosterone, begin to go down as early as the age of 30. Instead of plunging over a few years, the testosterone levels drop very slightly, for about 1% each year all throughout a man’s life. As this change is so gradual, many men may not become aware of any effects until more than a few decades have passed by.

Accordingly, because of the many incidences of men experiencing menopause symptoms, medical researchers were alarmed and consequently made some possible investigation on how to ease male menopause symptoms.

Thus, thorough studies were made on selective estrogen receptor modulators (SERMS) which are drugs that compete for the estrogen receptor and decrease the effects of estrogens on cells with those receptors. These drugs are informally called antiestrogens, and the category includes drugs such as tamoxifene, clomiphene, and toremiphene.

Basing on significant studies, Clomiphene was found out to boost testosterone levels by stimulating the body’s own production of testosterone. Hence, such drug was ultimately proven to be more effective and safer treatment for symptoms of andropause than testosterone replacement with Androgel or other testosterone products.

How Clomiphene Works

On clinical trials, 25mg of Clomiphene citrate increased testosterone levels two folds in men within one month. Also, the testosterone/estrogen ratio declined 40% as well. Similarly, there is significant increase in testosterone levels and improvement in sexual function with the use of Clomiphene citrate.

Clomiphene Side Effects

Unlike other testosterone replacement medications, Clomiphene and the like appear to have less possible side effects and are most likely more prostate “friendly” than other recent testosterone replacement products.

In addition, latest medications such as SERMS appear to have great potential to be effective yet have fewer risks, but results of larger recent clinical trials are necessary before final recommendations can be made.

Nevertheless, Clomiphene may be useful in elevating testosterone levels in men. However, it is not yet proven whether if these increases relate to improvement of menopause symptoms. And so, proper advice from medical specialists is still much suggested to men who appear to have menopause.

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